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AE_LETROZOLE

**Explain the risk of letrozole, such as arthralgia, headache, fatigue, mild emesis, hot flashes, abnormal LFTs, and osteoporosis **For the AE of bone loss of letrozole, regular exercise, adequate calcium and vitamin D intake are helpful (vitamin D3 1000 units daily is advisable) **Suggest closely follow-up clinical discomfort s/s and return to clinics if s/s progressed or any suspicious.

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