Dyslipidemias

• 1° (inherited causes): familial hyperchol. (1:250): defective LDL receptor; ↑↑ chol; ↑ CAD; familial hyperTG: ↑ TG & pancreatitis; familial combined hyperlipid.: ↑ chol & TG; etc.
• 2°: DM (↑ TG, ↓ HDL), hypothyroidism (↑ LDL, ↑ TG), nephrotic syndrome (↑ LDL, ↑ TG), liver failure (↓ LDL), alcohol (↑ TG, ↑ HDL), thiazides (↑ LDL, ↑ TG), protease inhib (↑ TG)

Explain by ChatGPT

• Dyslipidemias are disorders of lipid metabolism.
• There are two types of dyslipidemias: inherited and acquired.
  • Inherited dyslipidemias are caused by defects in genes that control lipid metabolism.
    • The most common inherited dyslipidemias are familial hypercholesterolemia and familial combined hyperlipidemia.
  • Acquired dyslipidemias can be caused by many factors, including

窩的英文不太好

-血脂異常是脂質代謝紊亂。 -血脂異常有兩種類型：遺傳性和獲得性。 -遺傳性血脂異常是由控制脂質代謝的基因缺陷引起的。最常見的遺傳性血脂異常是家族性高膽固醇血症和家族性複合型高脂血症。

• 獲得性血脂異常可由多種因素引起，包括糖尿病、甲狀腺功能減退症、腎病綜合徵、肝功能衰竭、酒精、噻嗪類藥物和蛋白酶抑製劑。

Backlink：

• Acquired dyslipidemias
• familial hypercholesterolemia
• lipid disorders
• protease inhibitors