Info

🌱 來自: Hemophagocytic lymphohistiocytosis

H-score

HScore for Reactive Hemophagocytic Syndrome

• 三個臨床加三對檢查
  • Hx.PE: 免疫 ✖ 不好、發燒、肝脾腫大
  • Lab: 1-{Bone Marrow, 血球低下}, 2-{Ferritin, Fibrinoten}, 3-{Tg, AST}

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• Known underlying immunosuppression
  • HIV positive or receiving long-term
  • immunosuppressive therapy (i.e., glucocorticoids, cycloSPORINE, azaTHIOprine)
• Temperature, “F (°C)
• Organomegaly
• Number of cytopenias
  • Defined as hemoglobin =9.2 g/dL (≤5.71 mmol/L) and/or WBC =5.000/mm° and/or platelets ≤110,000/mm?
• Ferritin, ng/mL (or ug/L)
• Triglyceride, mg/dL (mmol/L)
• Fibrinogen, mg/dL (g/L)
• AST, U/L
• Hemophagocytosis features on bone marrow aspirate → 161-170 40-54%