NOTE

🌱 created from: role_of_induction_chemotherapy-of-hnscc

rtog_91-11

• These 10-year results show that induction PF followed by RT and concomitant cisplatin/RT show similar efficacy for the composite end point of LFS.
• Locoregional control and larynx preservation were significantly improved with concomitant cisplatin/RT compared with the induction arm or RT alone.
• New strategies that improve organ preservation and function with less morbidity are needed

1.Forastiere AA, Zhang Q, Weber RS, et al. Long-term results of RTOG 91-11: a comparison of three nonsurgical treatment strategies to preserve the larynx in patients with locally advanced larynx cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2013;31(7):845-852. doi:10.1200/JCO.2012.43.6097