Info

Procalcitonin

  • ↑ in acute bacterial (not viral) PNA.
  • Consider stopping abx
    • if levels <0.25 ng/ml (<0.5 ng/mL in ICU Pts) or
    • ↓ ≥80% from peak.
  • ↓ abx exposure by 2–3 d
    • (Lancet ID 2016;16:819 & 2018;18:95).
  • Not validated in immunosuppressed hosts.
  • Levels harder to interpret in CKD.
  • False ⊕ in
    • cardiac arrest,
    • shock,
    • burns,
    • surgery.