Info

🌱 來自: rheumatology

systemic lupus erythematosus

• Definition and epidemiology 󰒖
• Classification Criteria 󰒖 (Ann Rheum Dis 2019;78:1151) for research/classification not dx
• Autoantibodies in SLE
• Workup 󰒖
• Treatment 󰒖
• Lupus nephritis Diagnosis and classification 🌟
• Prognosis (Nat Rev Rheumatol 2021;17:515)
  • Overall mortality 2-3× higher than general population, higher in Blacks.
  • Leading causes of morbidity/mortality:
    • infection,
    • CV events,
    • renal failure (nephritis remission achieved in <50%; >10% end up w/ ESRD),
    • neurologic events,
    • thrombosis
• Drug-induced lupus