Spondyloarthritis (SpA) Epidemiology and Key Presentation Features
Disease | Epidemiology |
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Ankylosing spondylitis (AS) | ♂:♀ = 3:1; onset in teens to mid-20s (rare after 40 y) |
Psoriatic arthritis (PsA) | ♂ = ♀; peak incidence 45-54 y; seen in 20-30% of Pts w/ psoriasis |
Reactive arthritis (ReA) | ♂ >> ♀; 20-40 y; 10-30 d after GI or GU infxn* in genetically susceptible host |
IBD-associated arthritis | ♂ = ♀; seen in 20% of IBD Pts; Crohn’s >UC |
Disease | Key Features |
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Ankylosing spondylitis (AS) | Progressive limitation of spinal motion, a.m. stiffness, buttock pain, “bamboo spine,” ⊕ Schober test |
Psoriatic arthritis (PsA) | In 13-17% arthritis precedes skin findings by yrs; does not correlate with psoriasis activity; a/w HIV |
Reactive arthritis (ReA) | Arthritis, urethritis, and conjunctivitis. Most resolve w/in 12 mo. |
IBD-associated arthritis | Type I <5 joints: correlates w/ IBD activ. Type II >5 joints or axial disease: does not correlate w/ IBD activity |