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🌱 來自: Important Antibacterial Drug Interactions

Rifampin of Important Antibacterial Drug Interactions

• Substrates of CYP3A4 (e.g., warfarin, ritonavir, cyclosporine, diazepam, verapamil, protease inhibitors, voriconazole)
• Substrates of CYP2C19 (e.g., omeprazole, lansoprazole)
• Substrates of CYP2C9 (e.g., warfarin, tolbutamide)
• Substrates of CYP2C8 (e.g., repaglinide, rosiglitazone)
• Substrates of CYP2B6 (e.g., efavirenz)
  • Can result in decreased levels of interacting drug. Avoid concomitant use if possible. If giving drugs concomitantly, monitor drug levels if possible.
• Hormone therapy (e.g., norethindrone)
  • Can result in decreased levels of hormone. If oral contraceptive and rifampin are given concomitantly, use alternative or additional forms of birth control.