Acute treatment-nephrolithiasis

(JAMA 2020;323:1961)

  • Analgesia (narcotics ± NSAIDs; combination superior, Ann Emerg Med 2006;48:173), ensure adequate fluid repletion, antibiotics if UTI

  • α-blocker >CCB to pass stone if ≤10 mm (Cochrane; 2014:CD008509, Lancet 2006;368:1171)

  • Indications for immediate urologic eval and/or hosp: obstruction (esp. solitary or transplant kidney), urosepsis, intractable pain or vomiting, significant AKI

  • Urologic Rx: lithotripsy (NEJM 2012:367:50), ureteroscopic removal, lap/perc nephrolithotomy