Treatment for acute HBV

• When to treat chronic HBV with anti-virals

• Entecavir or tenofovir

• hepatitis B virus Rx duration

• HBV Treatment

• If undergo liver transplant: HBIG + nucleo(s/t)ide analogue effective in preventing reinfection

• HIV/HBV coinfection: Rx w/ 2 drugs active against both HBV & HIV (https://aidsinfo.nih.gov)

• Immunosuppression: prior to initiating chemoRx, anti-TNF, rituximab, steroids (>20 mg/d >1 mo), screen for HBV; Rx if mod-to-high risk of reactive (incl anti-HBs ⊕ getting rituximab)

• Postexposure (risk infxn ~30%) Ppx: HBIG → vaccine (if unvac or known nonresponder)

Lamivudine、entecavir、telbivudine、tenofovir藥品之給付規定 󰒖