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🌱 來自: Huppert’s Notes

Depressed MoodSuicidal Ideation🚧 施工中

Depressed Mood/Suicidal Ideation

•   Definitions:

-   Suicidal ideation (SI)

   Active SI: Thoughts about acting to kill oneself with intent and/or plan (e.g., considering whether to shoot oneself with an owned gun, etc.)

   Passive SI: Thoughts about dying without intent and/or plan; an expression of despair/not wanting to be in a current mood, state, or situation (e.g., thoughts of “being better off dead,” thoughts of being hit by a car, etc.)

   Conditional SI: Thoughts of suicide that are dependent on specific conditions, such as satisfying a need, obtaining secondary gain, or remaining in the sick role (e.g., “If you don’t prescribe pain medications, I’m going to kill myself”)

-   Suicide attempt: Self-injury made in an attempt to kill oneself that does not result in fatality

-   Suicidal gesture: Self-injury made in an attempt to lead others to think that one wants to kill oneself even though there is no intention of dying; clinical feature of borderline personality disorder (e.g., holding a knife to one’s neck, putting a rope around one’s neck)

•   Risk factors for suicide: Prior attempts, psychiatric disease (>90% of patient who attempt), hopelessness, married, member of sexual minority, certain occupations, veterans, chronic pain, traumatic brain injury, access to firearms

•   Differential diagnosis for depressed mood:

-   Psychiatric disease:

   Major depressive disorder

   Bipolar disorder

   Anxiety disorders

   Personality disorders (e.g., borderline personality disorder)

   Post-traumatic stress disorder (PTSD)

   Psychotic disorders (e.g., schizophrenia)

   Substance use disorders

-   Other causes:

   Depression due to another medical condition

-   Cardiac disease

-   Malignancy (especially oropharyngeal and pancreatic)

-   Neurologic disease (including stroke, movement disorders)

-   Diabetes

-   Hypothyroidism

-   Chronic infection (including HIV, HCV)

   Depression due to medication effect

   Traumatic brain injury

   Chronic pain

   Malingering

•   Approach:

-   Safety assessment:

   Assess the suicidal ideation (i.e., passive vs. active; assess for plan, intent, means, lethality of means, rehearsal [i.e., elements of the plan being practiced, making preparations for one’s death])

   Assess protective factors (e.g., children or pets who rely on the person, loved ones who would be affected by their death, willingness to engage in safety planning/contingency planning for worsening symptoms, having hopes for the future [“future-oriented”], etc.)

   Assess for risk factors (see list of risk factors above), especially for prior suicide attempts

-   Assess for triggers/stressors

•   Work-up: CBC, BMP, LFTs, TSH (assess baseline organ function in anticipation of pharmacotherapy; rule out fatigue due to medical comorbidities, e.g., anemia or hypothyroidism mimicking depression). Consider additional testing based on exam/review of symptoms.

   Management:

-   Medical stabilization (if patient has attempted suicide and attempt was non-fatal) with involvement of psychiatry to make appropriate holding plan

-   Determine appropriate level of care (e.g., inpatient, day program, intensive outpatient therapy, outpatient): Inpatient hospitalization always indicated for recent attempt or high imminent risk (e.g., patients with plan/intent, poor social support, inability to discuss safety planning)

-   Create a safety plan

   Know warning signs and precipitants

   Secure/remove lethal agents

   Utilize individual coping strategies, such as reflecting on reasons to live, distraction activities, relaxation, and exercise

   Utilize interpersonal coping, such as friends or family who lift mood

   Create a list of professionals who can help and how to contact them

-   Initiate pharmacotherapy: See Table 13.3