Info

🌱來自: Management of follicular lymphoma

Management- Symptomatic Stages III–IV (or bulky Stage II), Front-line of follicular lymphoma

• Enrollment in clinical trial should be encouraged

• Commonly accepted indications for Rx include: Sx, any node >7 cm or 3 nodes >3 cm, cytopenias, fluid collections (ascites, pleural effusions), organ impairment & leukemic phase of disease (JCO 1998;16:2332)

• Multiple front-line therapeutic options.

  • Choice of Rx is based on pt & disease characteristics, including:
    • volume & distribution of disease,
    • age & functional status of the pt,
    • potential need for rapid response,
    • or concern for Histologic Transformation of follicular lymphoma

• Rituximab

• Obinutuzumab

• Maintenance and Consolidation Therapy of follicular lymphoma