Info

🌱 來自: Thalassemias

Dx of Thalassemias

MCV <70, normal Fe, ferritin, MCV/RBC count <13 [Mentzer Index, 60% Se, 98% Sp; (Ann Hem 2007;86:486)], ± ↑ retics, basophilic stippling; Hb electrophoresis: ↑ HbA2 (α2δ2) in β-thal; normal pattern in α-thal trait, ∴ PCR or supravital stain for dx

• MCV <70，
• 鐵、鐵蛋白正常
• MCV/RBC計數<13 Mentzer index，60％Se，98％Sp; (Ann Hem 2007;86:486)，
• ± ↑ retics
• 嗜鹼性斑點 basophilic stippling

Hb電泳：

• β-地中海貧血患者中α2δ2的HbA2↑，α地中海貧血特徵正常
• ∴需PCR或在體染色檢查進行診斷。