Info

Vanishing bile duct syndrome

  • Vanishing bile duct syndrome (VBDS) is → a rare but serious outcome and complication of drug induced liver injury marked clinically by chronic cholestasis and histologically by loss of intrahepatic bile ducts.
  • VBDS typically occurs after a bout of severe cholestatic hepatitis, often with immunoallergic features.

Etiologis

  • Chronic rejection of liver transplants
  • Sarcoidosis
  • Drugs