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colonoscopy of Screening of colorectal cancer
: preferred; 90% Se for lesions >1 cm. If polyp, re ✓ in 3–5 y. Adenomatous polyp removal a/w ↓ CRC mortality (NEJM 2012;366:687). Adenoma: ↑ risk of malig. if >2.5 cm, villous, or sessile; can progress to CRC over ~10 y interval (sporadic & familial).