Insulin Preparations

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Type(example)OnsetPeakDurationComments
Rapid(lispro, aspart)Immed1-2h<4hGive immediately before meal
Short(regular)~30 min2-3 h5-8 hGive ~30 min before meal
Intermed.(NPH)2-3 h4-8 h10-14hCan cause protamine Ab prod
Long(glargine, detemir)1-2 hn/a12-24 hOnce-daily basal insulin