Clinical manifestation-bacterial endocarditis

(Lancet 2016;387:882)

• Persistent bacteremia → fever (80–90%), rigors, night sweats, anorexia, myalgias
• Valvular or perivalvular infection → HF, conduction abnormalities (eg, AVB)
• Septic emboli: stroke, embolic MI, renal/splenic/pulmonary infarcts, septic arthritis, osteo
• Immune complex phenomena: arthritis, glomerulonephritis
• Subacute endocarditis can present with subacute progressive “B” sx (fatigue, wt loss)