Criteria-Hepatorenal syndrome (HRS)

(1) cirrhosis w/ ascites; (2) acute kidney injury (serum Cr ↑ ≥0.3 mg/dL w/in 48 h or ≥50% ↑ in serum Cr from baseline; Gut 2015;64:531) (3) Ø improvement in Cr after d/c diuretic & volume expansion (1 g/kg/d of albumin × 2 d); (4) Ø shock (prerenal azotemia/ATN); (5) Ø nephrotoxic meds; (6) Ø intrinsic kidney disease