hematopoietic stem cell transplantation

stem cell

Transplantation of donor pluripotent cells that can reconstitute all recipient blood lineages

• Stem Cell Transplant Basics
• mobility of hematopoietic stem cells
  • mobilization agent
• hematopoietic stem cell microenvironment
• graft-versus-host disease GVHD
• donor-specific

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類型、細胞來源、適應症、併發症、時機、預防

• categories of stem cell transplantation
  • Autologous Stem Cell Transplantation
  • allogeneic stem cell transplantation
• indications of hematopoietic stem cell transplantation
• transplantation procedure (for Allo HSCT)
• complications of hematopoietic stem cell transplantation
• timing of complications following allogeneic HSCT
• prophylaxis supportive medications during HSCT
• Post-transplant maintenance therapy
• Transplant Infection Prevention, Overview
• 2024-01-21-post-ASH

Chronic Active Antibody-Mediated Rejection (ABMR)

• Diagnosis requires:
  • Morphologic evidence of chronic tissue injury (e.g. transplant glomerulopathy)
  • Evidence of current or recent antibody interaction with the vascular endothelium (e.g. linear C4d staining of peritubular capillaries)
  • Serologic evidence of donor-specific antibody (DSA) formation.