Info

🌱 來自: treatment of metastatic colorectal cancer

Trifluridine and tipiracil

• Colorectal cancer, metastatic:
• Colorectal cancer, metastatic (single-agent therapy):
  • Oral:
    • 35 mg/m2/dose (based on the trifluridine component) twice daily on days 1 to 5 and days 8 to 12 of a 28-day cycle (maximum per dose: trifluridine 80 mg); continue until disease progression or unacceptable toxicity (Ref).
• Colorectal cancer, metastatic (combination therapy):
  • Oral:
    • 35 mg/m2/dose (based on the trifluridine component) twice daily on days 1 to 5 and days 8 to 12 of a 28-day cycle (in combination with bevacizumab; maximum per dose: trifluridine 80 mg); continue until disease progression or unacceptable toxicity