Info
Primary Regimens of Pneumocystis pneumonia, PJP, Adult
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Adult Treatment; Patient able to take po meds:
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TMP-SMX DS, 2 tabs po q8h x 21 days + Prednisone 15-30 minutes before starting anti-PJP therapy: 40 mg po q12h x 5 days, then 40 mg q24h x 5 days, then 20 mg q24h x 11 days
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(Dapsone 100 mg po q24h + TMP 5 mg/kg po q8h) x 21 days + Prednisone as above
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Adult Treatment; Patient not able to take po meds*:*
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TMP-SMX 15-20 mg of TMP component/kg/day IV divided q6-8h x 21 days (can switch to oral therapy once able to absorb meds) + Prednisone 15-30 minutes before starting anti-PJP therapy: 40 mg po q12h x 5 days, then 40 mg q24h x 5 days, then 20 mg q24h x 11 days
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Adult Prophylaxis: Primary prophylaxis/post-treatment of PJP suppression:
- TMP-SMX-DS 1 tab po q24h or 3x/week OR TMP-SMX-SS 1 tab po q24h
- Continue prophylaxis until CD4 count >200 for 3 months