Central diabetes insipidus

Arginine vasopressin deficiency (central diabetes insipidus): Treatment

polyuria, nocturia, and polydipsia

↓ ADH

  • Typically from mass lesion extrinsic to sella; pituitary tumor does not typically present w/ DI

  • Clinical manifestations: severe polyuria, thirst, nl to mild hyperNa (severe if ↓ access to H2O)

  • Diagnostic studies: see “Sodium and Water Homeostasis”

  • see overview-sodium and water homeostasis

  • see polyuria