Info
post-transplant_maintenance_therapy
- Lenalidomide
- maintenance improves PFS & OS for MM (JCO 2016 [suppl; abstr 8001]; NEJM 2014;371:895)
- Rituximab
- maintenance showed no benefit for DLBCL based on randomized phase III data
- (CORAL study, JCO 2010;28:4184), but showed PFS benefit in FL (EBMT LYM1 study, JCO 2013;31:1624) & PFS & OS benefit in MCL (particularly in younger pts) (NEJM 2017;377:1250)
- maintenance showed no benefit for DLBCL based on randomized phase III data
- BV
- maintenance in 1° refractory or unfav relapsed HL pts not previously exposed to BV showed PFS benefit in a randomized phase III study (AETHERA, Lancet 2015;385:1853)