Classification criteria of Behçet’s syndrome
(#1 + ≥2 others is 91% Se & 96% Sp; Lancet 1990;335:1078)
- Recurrent oral aphthous ulceration (≥3× in 1 y, usually 1st manifestation)
- Recurrent genital ulceration (labia in females, scrotum in males)
- Eye lesions: uveitis, scleritis, retinal vasculitis, optic neuritis; may threaten vision
- Skin lesions: pustules, papules, folliculitis, erythema nodosum (scarring)
- ⊕ pathergy test (prick forearm w/ sterile needle → pustule) (not sensitive in Caucasians)