Info
prechemo_breast
Education
- arranged Por-A implentation
- explained reason of adjuvant chemotherapy: cure and lower the risk of recurrence/metastasis.
- most likely metastasis sites: liver, brain, lung, bone.
- if metastasis, the 5-year survival rate is 26%
- explained chemotherapy schedule:
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CAF or AC followed by T- OPD setting, no need for hospitalization
- explained potential chemotherapy toxicities:
- common: fatigue, alopecia(reversible), nause/vomting, febrile neutropenia, opportunistic infection, infusion reaction (21% to 40% )
- cyclophosphamide: bone marrow function compromised, hemorrhagic cystitis, secondary leukemia ( 0.5% 千分之一)
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doxorubicin: cardiotoxicity, life-time culmucation 450-500 mg/BSA (___
240___
300mg/BSA throught this course)___
fluorouracil: stomatitis or esophagopharyngitis, leukopenia, vomiting, diarrhea, frequent bowel movements, watery stools, gastrointestinal ulcer or bleeding, hand-foot syndrome___
docetaxel: stomatitis, persistent febrile neutropenia, cutaneous reactions, moderate neurosensory effects, secondary leukemia ( 0.5% )
- explained potential endorcine therapy toxicities:
- AI: hot flashes, arthralgia, flushing, asthenia, edema, headache, osteoporosis and fractures, hypercholesterolemia, hepatic impairment
- explained potential ICI toxicities:
- pembrolizumab: skin rash pneumonitis, colitis, hepatitis, hypophysitis, thyroid dysfunction, diabetes mellitus
- suggested high protein diet, not suggested additional supplement because it may confound the lab, which may lead to postponed the chemotherapy schedule.
- informed patient to avoid raw food, include fish, meat, vegetable