Info

prechemo_breast

Education

  • arranged Por-A implentation
  • explained reason of adjuvant chemotherapy: cure and lower the risk of recurrence/metastasis.
    • most likely metastasis sites: liver, brain, lung, bone.
    • if metastasis, the 5-year survival rate is 26%
  • explained chemotherapy schedule: ___ CAF or AC followed by T
    • OPD setting, no need for hospitalization
  • explained potential chemotherapy toxicities:
    • common: fatigue, alopecia(reversible), nause/vomting, febrile neutropenia, opportunistic infection, infusion reaction (21% to 40% )
    • cyclophosphamide: bone marrow function compromised, hemorrhagic cystitis, secondary leukemia ( 0.5% 千分之一)
    • ___ doxorubicin: cardiotoxicity, life-time culmucation 450-500 mg/BSA ( ___ 240 ___ 300mg/BSA throught this course)
    • ___ fluorouracil: stomatitis or esophagopharyngitis, leukopenia, vomiting, diarrhea, frequent bowel movements, watery stools, gastrointestinal ulcer or bleeding, hand-foot syndrome
    • ___ docetaxel: stomatitis, persistent febrile neutropenia, cutaneous reactions, moderate neurosensory effects, secondary leukemia ( 0.5% )
  • explained potential endorcine therapy toxicities:
    • AI: hot flashes, arthralgia, flushing, asthenia, edema, headache, osteoporosis and fractures, hypercholesterolemia, hepatic impairment
  • explained potential ICI toxicities:
    • pembrolizumab: skin rash pneumonitis, colitis, hepatitis, hypophysitis, thyroid dysfunction, diabetes mellitus
  • suggested high protein diet, not suggested additional supplement because it may confound the lab, which may lead to postponed the chemotherapy schedule.
  • informed patient to avoid raw food, include fish, meat, vegetable