Info

tumor proportion score

  • TPS:
    • Based on the proportion of tumor cells that express PD-L1 to the total number of tumor cells (staining and non-staining)
    • Only evaluates PD-L1 expression in tumor cells
  • CPS:
    • Similar to TPS, but includes
      • PD-L1 expression in
        • tumor-associated lymphocytes and macrophages
    • ratio of PD-L1 positive tumor cells
      • to total tumor cells
    • Evaluates PD-L1 expression in both tumor cells and non-tumor cells