Dose-dense MVAC chemotherapy for urothelial carcinoma
Keyword: ddMVAC [Dose-dense MVAC chemotherapy for urothelial carcinoma - UpToDate](https://www.uptodate.com/contents/image?imageKey=ONC%2F111814&topicKey=ONC%2F3000&source=see link)
durg:
- methotrexate
- vinblastine
- doxorubicin
- cisplatin
Pretreatment considerations:
- 吐: 高
- vesicant/irritant properties
- Infection prophylaxis: 高 G-CSF: 240mcg/m2 SC daily on d4-d10
Monitor Parameters:
CBC/Electrolytes/Neurologic/3rd space fluid collection/LVEF
- hearing loss of cisplatin