MI in absence of obstructive CAD

  • Definition:
    • MI but w/o coronary stenosis ≥50% in any major epicardial vessel
  • More common
    • in younger Pts,
    • women,
    • Black/Pacific race or Hispanic
  • Advanced coronary imaging (eg, OCT) & cardiac MRI to exclude missed coronary obstruction, other causes of myocyte injury (eg, myocarditis), other causes of ↑ Tn (eg, PE)
  • ~75% ischemic (ie, plaque disruption identified) and 25% alternative dx (eg, myocarditis)