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🌱 來自: peripheral artery disease

Clinical features-peripheral artery disease

(NEJM 2016;374:861, Circ 2021;144:e171)

• Prev. ↑ w/ age:
  • <1% if <40 y, ~15% if ≥70 y;
  • risk factors incl.
    • smoking,
    • DM,
    • HTN,
    • chol
• Claudication (ache/cramp, often in calves) precip by walking and relieved by stopping (vs. spinal stenosis, qv);
• Leriche syndrome
• Critical limb ischemia (CLI):
  • rest pain (↑ w/ elevation b/c ↓ perfusion), ulcer (typically at ↣ pressure foci, often dry;
  • in contrast, venous ulcers are more often at ↣ medial malleolus, wet, and with hemosiderin deposition) or gangrene, due to PAD, and >2-wk duration (implies chronicity vs. acute limb ischemia; see below) (Circ 2019;140:e657)