Info
diagnostic evaluation of waldenstrom’s macroglobulinemia (WM)
- SPEP + immunofixation with IgM >3 g/dL
- 24-h urine for UPEP (only 20% have ⊕ UPEP)
- Bone marrow biopsy:
- ↑ plasmacytoid lymphocytes;
- β2-microglobulin for prognostic eval
- Relative serum viscosity:
- ratio serum viscosity to H2O (nl 1.8);
- hyperviscosity when >5–6