nucleoside reverse transcriptase inhibitor NRTI-Antiretrovirals (ARVs)

Class: GI intol, lipoatrophy, lactic acidosis

abacavir (ABC; Ziagen)

ABC: hypersensitivity (3%), ✓ HLA-B*5701

emtricitabine (FTC; Emtriva)

lamivudine (3TC; Epivir)

tenofovir (TAF or TDF)

TDF: renal toxicity, bone density loss TAF: minimal renal toxicity

zidovudine (AZT; Retrovir)

AZT: BM suppression (esp. macrocytic anemia)