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General Management Principles of metastatic breast cancer

  • Goal of treatment: ↑ survival, ↓ symptoms, ↑ QoL
  • Give systemic therapy (endocrine, chemo, targeted);
  • local intervention (eg, surgery/RT) for symptomatic control & imminent organ threat (eg, bone pain, cord compression, brain met)
  • Treatment typically continued until tox or POD
  • Consider clinical trial