Info 🌱 來自：Treatment of unresectable and metastatic GIST Sunitinib Multitargeted TKI; second line tx after imatinib failure; good activity in exon 9, 13/14 Mts RCT sunitinib vs. placebo in imatinib-resistant GIST, sunitinib ↑ PFS/OS, RR ∼10% (Lancet 2006;368:1329)