Treatment-fever of unknown origin

• Empiric abx not indicated (unless Pt neutropenic or critically ill)
• Empiric glucocorticoids not indicated unless strong suspicion for specific rheumatologic dx
• Stop unnecessary meds (only 20% with a med cause have eos or rash)
• Up to 30% of cases remain undiagnosed, most spontaneously defervesce (wks to mos)