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🌱 來自: Mechanisms and Etiologies of Platelet Function Abnormalities

Acquired Platelet Function Disorders

• Adhesion defects
  • Uremia,
  • acquired vWD (often due to underlying LPD)
• Aggregation defects
  • Medications:
    • Ticlopidine,
    • clopidogrel,
    • GP IIb/IIIA antagonists,
    • high dose β-lactam abx,
    • SSRI,
    • herbal supplements Dysproteinemias: Myeloma,
    • amyloidosis
• Granule defects
  • MPN
  • acute leukemias,
  • liver dz,
  • cardiopulmonary bypass Medications: ASA,
  • NSAIDs,
  • SSRI