Prognosis-acute liver failure

(Ann Intern Med 2016;164:724; World J Gastro 2016;22:1523)

  • Non-acetaminophen ALF mortality ~70%, acetaminophen-induced ALF mortality ~25–30%

  • HBV, Wilson’s, AIH, DILI, Budd-Chiari ~ associated with ↓ prognosis

  • Factor V level <20% in Pts <30 yrs or <30% in >30 yrs associated w/ poor prognosis