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🌱 來自: nephrotic syndrome

Classification of Nephrotic Syndrome

• The major forms of nephrotic syndrome, based on biopsy:
  • minimal-change disease (more common in children) TLDR: MCD
    • 光學看 ✖ 不到，電顯看得到
    • primary and
    • secondary (e.g., as a paraneoplastic condition)
  • focal segmental glomerulosclerosis TLDR: FSGS
    • Diffuse vs Focal : 整個腎臟中 是: 每個腎絲球都有問題還 是: 部分腎絲球有問題
    • Global vs Segmental : 同一個腎絲球裡 是: 全部有問題還 是: 部分區域有問題
    • primary
    • secondary (e.g., HIV, toxins, vasculitis, lupus)
  • membranous nephropathy TLDR: MN
    • primary TLDR: PLA2R, THSD7A
      • M-type phospholipase A2 receptor PLA2R
      • thrombospondin type 1- domain-containing 7A THSD7A
    • secondary TLDR: HBV, HCV, lupus, NSAID, Malig
      • associated with hepatitis B and C,
      • nonsteroidal anti-inflammatory drugs: NSAIDS
      • lupus, malignancy
  • diabetes mellitus (diabetic nephropathy)
  • amyloidosis
  • lupus