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GIST 2

Jan 01, 20242 min read

date: “2023-12-05--- title: “GIST” date: “2023-12-05 09:57:35” enableToc: false tags:

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GIST

GIST of stomatch body (distal jejunum (18cm, mitotic count 2-5/5 mm2, low mitotic count, prognostic group 3b, pT4Nx)) s/p laparoscopic assisted partial gastrectomy on 2017/9/28, high risk, DFS 88%

  • Initial presentation: palpable abdominal mass for 3 months
  • Explain optional self-paid adjuvant imatinib for 3 years due to high risk to reduce local recurrence and distant mets but not 100 percent, HR 0.45 if taking imatinib for up to 3 years @ Explain AEs of imatinib @ Start imatinib 400mg QD on 10/24, RTC on 10/24 for drug and check lab @ KBT for possible diarrhea @ Pharmacist education later **nausea and vomiting (40-50%), mild to moderate transient ankle and periorbital edema, occasional myalgias, fluid retention with pleural effusion, ascites, pulmonary edema, and weight gain, diarrhea (25-30%), myelosuppression (weekly⇒biweekly⇒periodically), erythema multiforme and possible Stevens-Johnson syndrome but rare

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