Etiology-osteomyelitis

(Lancet 2004;364:369)

• Hematogenous: S. aureus; mycobacterial infection of vertebral body = Pott’s disease
• Contiguous focus (may be acute or chronic)
  • Open fracture, orthopedic surgery, etc.: S. aureus and S. epi
  • Skin breakdown + vasc. insuffic. (eg, diabetic foot, pressure ulcer): polymicrobial
  • GU source (GNR, Enterococcus)