Info

🌱來自: hepatocellular carcinoma

Risk factors of hepatocellular carcinoma

(globally, 3rd leading cause of cancer death, espec. in Africa & Asia)

• Cirrhosis: present in 70–90% HCC cases
• Infectious: HCV & HBV (~75%), HBV/HDV coinfection; HBV can cause HCC w/o cirrhosis
• Toxic: EtOH (⅓ cases in U.S.), tobacco, aflatoxin from Aspergillus
• Metabolic disorders: NASH, diabetes mellitus, autoimmune hepatitis, hemochromatosis