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🌱 來自: bladder cancer

etiology and clinical manifestations-of-bladder cancer

  • RFs:
    • Smoking
    • aromatic amines,
    • occupational exposures
      • (metal, paint, rubber, leather, textile),
    • chronic infxns,
    • cyclophosphamide,
    • RT; Hereditary: Lynch syn
  • Presenting sxs:
    • Painless hematuria (typically intermittent & gross),
    • irritative voiding sx (frequency, urgency, dysuria),
    • flank or suprapubic pain (symptomatic of locally advanced dz),
    • constitutional sx (fatigue, wt loss, failure to thrive) usually symptomatic of met dz