Info

Breast cancer main pathway

W/u

  • CBC
  • CEA, CA15-3
  • Liver function test
  • Chest x-ray
  • Mammography
  • Ultrasonography of both breasts
  • Pathology review
  • Ultrasonography of liver ***

Wide excision or Mastectomy

ALND or SLNB

N postive or negative ⊕ ⊖

  1. Tamoxifen as the drug of choice. If intolerable side effect, consider aromatase inhibitor.
  2. adjuvant Herceptin for patients with HER2 over-expression, node(-), tumor size > 1 cm, after adjuvant chemotherapy.
  3. CMF x8 : optional for old-aged or with other co-morbidities. TC x6: optional for patient to avoid cardiac toxicity and want to omit anthracycline..