Info

Prognostic Factors

  • Worse if poor PS, relapse-free interval ≤2 yrs from adj Rx,↑ sites of dz, ↑ prior treatments, presence of circulating tumor cells (≥5 CTCs per 7.5 mL whole blood)
  • Race: 5 yr OS overall is 26%, worse in AA c/w Caucasian (18 vs. 27%)
  • Site of dz: Better w/nonviscera (bone, CW, LN); worse w/viscera or CNS
  • Incurable; no os benefit of early dz w/surveillance after rx of 1° (jama 1994; 271:1593)