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🌱 來自：head_and_neck_squamous_cell_cancer

esmo_checklist_hnscc_patient_related_treatment_workflow

• MEDICAL HISTORY AND RISK FACTORS
• PRESENT MEDICAL CONDITIONS
• DIAGNOSIS AND CLINICAL STAGING
• HISTOLOGICAL ANALYSIS
• MDT DISCUSSION AND DECISION (PRIMARY MALIGNANCY CENTERED)
• MDT DISCUSSION AND DECISION (TREATMENT SUPPORT CENTERED)

MEDICAL HISTORY AND RISK FACTORS

• Past personal medical history and vascular risk factors:
• Past surgical history:
• Concurrent medication:
• Allergies:
• Smoking history: pack/y from age to age
• Alcohol consumption:
• Normal weight: Height: BMI:

PRESENT MEDICAL CONDITIONS

• Main symptoms:
• Nutritional status:
• Speech and swallow function:
• Dental status:
• Psycho-social evaluation:
• Geriatric assessment (if indicated)
• Other relevant clinical conditions (autoimmune disease, renal impairment, etc.):

DIAGNOSIS AND CLINICAL STAGING

• Physical examination (including H&N areas):
• H&N endoscopy:
• H&N CE-CT and/or MRI:
• FDG-PET-CT scan:
• TNM stage and grade:
  • Location:
    • Oral cavity
    • Oropharynx
    • Hypopharynx
    • Larynx
    • Unknown
  • Disease extension:
    • Local disease
    • Locoregional disease
    • Metastatic disease

HISTOLOGICAL ANALYSIS

• Core biopsy of primary tumor:
  • Squamous cell carcinoma
  • Other histology
• Surgical specimen:
  • Tumor size (mm)
  • Growth pattern
  • Depth of invasion /DOI (mm) (oral cavity)
  • Lymphatic infiltration (y/n)
  • Perineural infiltration (y/n)
  • Surgical margins (positive/negative)
• Lymph node evaluation:
  • Nº removed
  • Nº affected and location
  • Extracapsular extension (y/n)
• Biomarker analysis:
  • HPV status (oropharynx)
  • PDL1- CPS (R/M disease)
  • EBV status (if unknown primary)
• Tissue material available/stored for future molecular analyses: YES NO

MDT DISCUSSION AND DECISION (PRIMARY MALIGNANCY CENTERED)

• Surgery
• Adjuvant radiotherapy
• Adjuvant Chemoradiotherapy
• Definitive radiotherapy (early-stage disease)
• Definitive Chemoradiotherapy
• Definitive Bioradiotherapy (cetuximab)
• Induction chemotherapy followed by Chemo/bioradiotherapy
• Systemic therapy for advanced disease
• Supportive and palliative care
• Enrolment in a clinical trial

MDT DISCUSSION AND DECISION (TREATMENT SUPPORT CENTERED)

• Need of upper-airway support
• Need of nutritional support
• Need of dental support
• Need of speech and swallow support
• Need of psycho-social support

My templated

schedule supportive care: airway assessment, nutritional support, dental care, speech and swallow testing, and psycho-social support.