NOTE

🌱 created from: cytogenetic_of_all

poor_risk_cytogenetic_of_all

  • Hypodiploidy (<44 chromosomes)
  • TP53 mutation
  • KMT2A rearranged (t[4;11])
  • IgH rearranged
  • HLF rearranged
  • ZNF384 rearranged
  • MEF2D rearranged
  • MYC rearranged
  • PAX5alt
  • t(9;22) with IKZF1 plus and/or antecedent CML
  • Complex karyotype (5 or more chromosomal abnormalities)
  • BCR-ABL1-like (JAK-STAT, ABL class, other etc)
  • Intrachromosomal amplifcation of chromosome 21
  • Alterations of IKZF1