Treatment prevention-herpes zoster

• Uncomplicated: acyclovir, valacyclovir, or famciclovir x 7 d; initiate w/in 72 h of onset for greatest benefit; consider after 72 h if new lesions present; minimal benefit after crusting
• Superimposed bacterial cellulitis is common; if suspected, treat with appropriate antibiotics
• Disseminated/immunosupp.: IV acyclovir, eval for visceral spread, droplet precautions
• Prevention: Shingrix (2 doses) for all Pts >50; consider in younger if immunosupp.