Info
diagnostic evaluation of small lymphocytic lymphoma
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CBC w/ diff: B-cell count
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Peripheral smear: lymphocytosis (predominantly mature-appearing small cells) “smudge” cells from damage to abnl lymphs from shear stress of making blood smear
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Flow cytometry: clonality with dim surface Ig; CD5+, CD19+, CD20+, CD23+
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Bone marrow (not req for dx): normo- or hypercellular; ≥30% small B lymphocytes