Info

🌱 來自: inflammatory myopathies

Autoantibodies of inflammatory myopathies

• ⊕ anti-Jo-1 (25%): most common specific Ab; a/w antisynthetase syndrome
• ⊕ anti-Mi-2 (DM >PM 15-20%) is → a/w disease that responds well to steroids
• ⊕ anti-SRP is → a/w NM, poor Rx response; ⊕ anti-HMGCR in NM a/w statin exposure
• Multiple others (Best Pract Res Clin Rheumatol 2018;32:887). Often ordered as an Ab panel.