Info

🌱 來自: Etiologies-Aplastic anemia

Shortened telomeres

seen w/ telomerase (TERT, TERC) mut

• (10% of aplastic anemia),
• dyskeratosis congenita/DKC1 mut;
• a/w IPF, cirrhosis (NEJM 2009;361:2353)

in genes

• GATA2
• RUNX1
• MPL can present as marrow failure in normal-appearing adults.