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🌱 來自: Multiple Endocrine Neoplasia

gastrointestinal neuroendocrine tumors

Tumor Type	Symptoms	Treatment
Gastrinoma	Zollinger-Ellison syndrome: gastroesophageal reflux, peptic ulcer disease, diarrhea	Proton pump inhibitors, somatostatin analogues
Insulinoma	Hypoglycemia leading to confusion, lethargy, coma; weight gain	Diazoxide, everolimus
Glucagonoma	Skin rash (necrolytic migratory erythema), glucose intolerance, weight loss	Somatostatin analogues
VIPoma	Verner-Morrison syndrome: watery diarrhea, hypokalemia, achlorhydria	Somatostatin analogues
ACTHoma	Cushing’s syndrome: hyperglycemia, weight gain, hypokalemia	Ketoconazole, consider adrenalectomy

• Zollinger-Ellison
• Cushing